RNase L-IN-2
Names
[ CAS No. ]:
357618-26-9
[ Name ]:
RNase L-IN-2
[Synonym ]:
[1]Benzothieno[2,3-d]pyrimidin-4(3H)-one, 5,6,7,8-tetrahydro-2-(3-hydroxyphenyl)-
2-(3-Hydroxyphenyl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
MFCD02212163
Biological Activity
[Description]:
RNase L-IN-2 is a small-molecule activator of RNase L with EC50 of 22 uM; shows broad-spectrum antiviral activity against diverse types of RNA viruses, including the human pathogen human parainfluenza virus type 3, with no cytotoxic at the effective concentrations.
[References]
References 1. Thakur CS, et al. Proc Natl Acad Sci U S A. 2007 Jun 5;104(23):9585-90. View Related Products by Target Other Targets
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Molecular Formula ]:
C16H14N2O2S
[ Molecular Weight ]:
298.360
[ Exact Mass ]:
298.077606
[ LogP ]:
3.09
[ Index of Refraction ]:
1.781
Safety Information
[ Hazard Codes ]:
Xi