KH 7
Names
[ CAS No. ]:
330676-02-3
[ Name ]:
KH 7
[Synonym ]:
Propanoic acid, 2-(1H-benzimidazol-2-ylthio)-, 2-[(1E)-(5-bromo-2-hydroxyphenyl)methylene]hydrazide
2-(1H-Benzimidazol-2-ylsulfanyl)-N'-[(E)-(5-bromo-2-hydroxyphenyl)methylene]propanehydrazide
MNI-caged-L-glutamate
KH7
(E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: 3-10 μM (recombinant sACt)[1].
[References]
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Molecular Formula ]:
C17H15BrN4O2S
[ Molecular Weight ]:
419.296
[ Exact Mass ]:
418.009888
[ PSA ]:
115.67000
[ LogP ]:
6.01
[ Index of Refraction ]:
1.716
[ Storage condition ]:
2-8℃
MSDS
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301
[ Precautionary Statements ]:
P301 + P310
[ RIDADR ]:
UN 2811 6.1 / PGIII
Articles
J. Immunol. 194 , 5472-87, (2015)
PGE2 is a potent lipid mediator involved in maintaining homeostasis but also promotion of acute inflammation or immune suppression in chronic inflammation and cancer. Nucleotide-binding domain, leucin...
Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.J. Exp. Med. 212 , 1021-41, (2015)
CD99 is a critical regulator of leukocyte transendothelial migration (TEM). How CD99 signals during this process remains unknown. We show that during TEM, endothelial cell (EC) CD99 activates protein ...
Short- and long-term regulation of intestinal Na+/H+ exchange by Toll-like receptors TLR4 and TLR5.Am. J. Physiol. Gastrointest. Liver Physiol. 309 , G703-15, (2015)
Inappropriate activation of pattern recognition receptors has been described as a potential trigger in the development of inflammatory bowel disease (IBD). In this study, we evaluated the activity and...