Prednisolone hemisuccinate
Names
[ CAS No. ]:
2920-86-7
[ Name ]:
Prednisolone hemisuccinate
[Synonym ]:
MFCD00056465
PREDNISOLONE HEMISUCCINATE
PREDNISOLONE 21-HEMISUCCINATE
prednisolone21-succinate
prednisolonbisuccinat
EINECS 220-861-8
prednisolut
prednisolon hemisuccinate
Prednisolone hemisuccinate (usp)
prednisolonebisuccinate
Prednisolone (hemisuccinate)
Biological Activity
[Description]:
[Related Catalog]:
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
0,86 g/cm3
[ Boiling Point ]:
358 °C400 mm Hg(lit.)
[ Melting Point ]:
28-32 °C(lit.)
[ Molecular Formula ]:
C25H32O8
[ Molecular Weight ]:
460.51700
[ Flash Point ]:
265°C/15mm
[ Exact Mass ]:
460.21000
[ PSA ]:
138.20000
[ LogP ]:
1.97330
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.6
[ Storage condition ]:
2-8℃
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TU4153400
- CHEMICAL NAME :
- Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-, 21-(hydrogen succinate)
- CAS REGISTRY NUMBER :
- 2920-86-7
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C25-H32-O8
- MOLECULAR WEIGHT :
- 460.57
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 50 mg/kg
- SEX/DURATION :
- female 13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,216,1986
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 75 mg/kg
- SEX/DURATION :
- female 13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - homeostasis
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,216,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9553 No. of Facilities: 403 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4029 (estimated) No. of Female Employees: 2015 (estimated)
Safety Information
[ Risk Phrases ]:
61-40
[ Safety Phrases ]:
S53-S22-S36/37/39-S45
[ RIDADR ]:
NONH for all modes of transport
[ RTECS ]:
TU4153400