(2H3)Methionine

Names

[ Name ]:
(2H3)Methionine

[Synonym ]:
Methionine-d
(H)Methionine

Biological Activity

[Description]:

DL-Methionine-d3 is the deuterium labeled DL-Methionine. DL-Methionine is an essential amino acid containing sulfur with oxidative stress defense effects. DL-Methionine can be used for animal natural feed. DL-Methionine also kills H. rostochiensis on potato plants[1][2][3][4].

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. K. evans, et al. Effects of amino acids on the reproduction of Heterodera rostochiensis. Nematologica, 1971, 17(4), 495-500.

[3]. Swennen Q, et al. Effects of dietary protein content and 2-hydroxy-4-methylthiobutanoic acid or DL-methionine supplementation on performance and oxidative status of broiler chickens. Br J Nutr. 2011 Dec;106(12):1845-54.

[4]. Garlich JD. Response of broilers to DL-methionine hydroxy analog free acid, DL-methionine, and L-methionine. Poult Sci. 1985 Aug;64(8):1541-8.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
306.9±37.0 °C at 760 mmHg

[ Melting Point ]:
280ºC (dec.)(lit.)

[ Molecular Formula ]:
C₅H₈D₃NO₂S

[ Molecular Weight ]:
152.23

[ Flash Point ]:
139.4±26.5 °C

[ Exact Mass ]:
152.069885

[ PSA ]:
88.62000

[ LogP ]:
0.37

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.531

Related Compounds

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