5-fluoro-1-[(2R,4R)-4-(hydroxymethyl)-7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-2-yl]pyrimidine-2,4-dione

Names

[ Name ]:
5-fluoro-1-[(2R,4R)-4-(hydroxymethyl)-7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-2-yl]pyrimidine-2,4-dione

[Synonym ]:
5-fluoro-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)dione
5-fluorouridine-2,3-isopropylidene derivative
5-Fluoro-2',3'-O-(1-methylethylidene)uridine
5-Fluoro-2',3'-isopropylideneuridine
5-fluoro-1-[(2R,4R)-4-(hydroxymethyl)-7,7-dimethyl-3,6,8-trioxabicyclo[3.3.0]oct-2-yl]pyrimidine-2,4-dione
5-Fluoro-2',3'-O-isopropylideneuridine

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Melting Point ]:
196-198ºC

[ Molecular Formula ]:
C₁₂H₁₅FN₂O₆

[ Molecular Weight ]:
302.25600

[ Exact Mass ]:
302.09100

[ PSA ]:
102.78000

[ Index of Refraction ]:
1.585

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YU8051000

CHEMICAL NAME :: Uridine, 5-fluoro-2',3'-O-(1-methylethylidene)-

CAS REGISTRY NUMBER :: 2797-17-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H15-F-N2-O6

MOLECULAR WEIGHT :: 302.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 725 umol/L

REFERENCE :: CCCCAK Collection of Czechoslovak Chemical Communications. (Academic Press Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK) V.1- 1929- Volume(issue)/page/year: 43,3268,1978