RIPK1-IN-9

Names

[ CAS No. ]:
2682889-57-0

[ Name ]:
RIPK1-IN-9

Biological Activity

[Description]:

RIPK1-IN-9 (example 45), a dihydronaphthyridone compound, is a potent and selective RIPK1 inhibitor. RIPK1-IN-9 inhibits U937 cell (IC50=2 nM) and L929 cell (IC50=1.3 nM)[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> RIP kinase
Research Areas >> Inflammation/Immunology

[References]

[1]. Fusheng Zhou, et al. Dihydronaphthyridone compounds, their preparation and pharmaceutical uses. WO2021160109A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H25FN6O2

[ Molecular Weight ]:
472.51

Related Compounds