Calenduloside E

Names

[ Name ]:
Calenduloside E

[Synonym ]:
Momordin Ib
Glycoside St-E
Polysciasaponin P7
Silphioside F
Olean-12-en-28-oic acid, 3-(β-D-glucopyranuronosyloxy)-, (3β)-
(3β)-28-Hydroxy-28-oxoolean-12-en-3-yl β-D-glucopyranosiduronic acid
Oleanolic acid 3-O-glucuronide
Scheffleraside I
oleanolic acid 3-O-β-D-glucosiduronic acid

Biological Activity

[Description]:

Calenduloside E (CE) is a natural pentacyclic triterpenoid saponin extracted from Aralia elata. Calenduloside E (CE) has anti-apoptotic potent by targeting heat shock protein 90 (Hsp90)[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> HSP

Signaling Pathways >> Cell Cycle/DNA Damage >> HSP

[References]

[1]. Tian Y, et al. The clickable activity-based probe of anti-apoptotic calenduloside E. Pharm Biol. 2019 Dec;57(1):133-139.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
750.8±60.0 °C at 760 mmHg

[ Melting Point ]:
243-245 ºC (decomp)

[ Molecular Formula ]:
C₃₆H₅₆O₉

[ Molecular Weight ]:
632.824

[ Flash Point ]:
228.6±26.4 °C

[ Exact Mass ]:
632.392456

[ PSA ]:
153.75000

[ LogP ]:
7.04

[ Vapour Pressure ]:
0.0±5.7 mmHg at 25°C

[ Index of Refraction ]:
1.590

[ Water Solubility ]:
Insuluble (2.2E-4 g/L) (25 ºC)

Precursor & DownStream

Precursor

DownStream

Related Compounds

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