disulfoton-oxon-sulfoxide
Names
[ CAS No. ]:
2496-92-6
[ Name ]:
disulfoton-oxon-sulfoxide
[Synonym ]:
O,O-Diethyl S-ethyl-2-ethylmercaptophosphorothiolate sulfoxide
PO systox sulfoxide
Thiol-demeton-sulfoxid
Systox-thiol-sulfoxid
Thiol systox sulfoxide
Isodemeton-sulfoxide
Isosystox sulfoxide
Chemical & Physical Properties
[ Density]:
1.241g/cm3
[ Boiling Point ]:
401.4ºC at 760mmHg
[ Molecular Formula ]:
C8H19O4PS2
[ Molecular Weight ]:
274.33800
[ Flash Point ]:
196.6ºC
[ Exact Mass ]:
274.04600
[ PSA ]:
106.92000
[ LogP ]:
3.53500
[ Vapour Pressure ]:
2.74E-06mmHg at 25°C
[ Index of Refraction ]:
1.512
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TF2850000
- CHEMICAL NAME :
- Phosphorothioic acid, O,O-diethyl S-(2-(ethylsulfinyl)ethyl)ester
- CAS REGISTRY NUMBER :
- 2496-92-6
- BEILSTEIN REFERENCE NO. :
- 1712527
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C8-H19-O4-P-S2
- MOLECULAR WEIGHT :
- 274.36
- WISWESSER LINE NOTATION :
- OS2&2SPO&O2&O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 234,352,1958
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 ug/kg
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
- REFERENCE :
- AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 13,606,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PAREAQ Pharmacological Reviews. (Williams & Wilkins, 428 E. Preston St., Baltimore, MD 21202) V.1- 1949- Volume(issue)/page/year: 11,636,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 5000 ug/kg
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
- REFERENCE :
- AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU. Volume(issue)/page/year: 13,606,1956
Safety Information
[ RIDADR ]:
UN 3018
[ Hazard Class ]:
6.1(a)