α-Synuclein inhibitor 6

Names

[ CAS No. ]:
2489813-02-5

[ Name ]:
α-Synuclein inhibitor 6

Biological Activity

[Description]:

α-Synuclein inhibitor 6 (compound 3ge) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.70 μM and inhibition ratio at 30 μM of 94.4%[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[Target]

IC50: 1.70 ± 0.69 μM (α-Synuclein)[1]


[References]

[1]. Chen L, et al. Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro α-synuclein aggregation. Bioorg Med Chem. 2020 Aug 1;28(15):115596.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H15FN2O5

[ Molecular Weight ]:
382.34

Related Compounds