Carbonic anhydrase inhibitor 13

Names

[ CAS No. ]:
2488872-31-5

[ Name ]:
Carbonic anhydrase inhibitor 13

Biological Activity

[Description]:

Carbonic anhydrase inhibitor 13 (compound 7) is a potent carbonic anhydrase (CA) inhibitor, which features 3-methylthiazolo[3,2-a]benzimidazole moiety (as a tail) connected to the zinc anchoring benzenesulfonamide moiety via ureido linker[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[References]

[1]. Alkhaldi AAM, et al. 3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies. Eur J Med Chem. 2020 Dec 1;207:112745.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H15N5O3S2

[ Molecular Weight ]:
401.46

Related Compounds