Carbonic anhydrase inhibitor 6

Names

[ CAS No. ]:
1013213-84-7

[ Name ]:
Carbonic anhydrase inhibitor 6

Biological Activity

[Description]:

Carbonic anhydrase inhibitor 6 (compound 9b) is a potent inhibitor of human carbonic anhydrase (hCA), with Kis of 9.7 nM, 35.2 nM, 88.5 nM, and 91.8 nM for hCA IX, hCA II, hCA XII and hCA I, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[References]

[1]. Swain B, et, al. Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases. Eur J Med Chem. 2022 Apr 15;234:114247.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H25N3O5S

[ Molecular Weight ]:
491.56

Related Compounds