JAK2/STAT3-IN-1

Names

[ CAS No. ]:
2485758-50-5

[ Name ]:
JAK2/STAT3-IN-1

Biological Activity

[Description]:

JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> Interleukin Related

[Target]

IC50: 3.04 µM (GP130)[1]


[References]

[1]. Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375.

Chemical & Physical Properties

[ Molecular Formula ]:
C34H35BrF3N5O2

[ Molecular Weight ]:
682.57

Related Compounds