JAK2-IN-4

Names

[ CAS No. ]:
1438284-00-4

[ Name ]:
JAK2-IN-4

Biological Activity

[Description]:

JAK2-IN-4 (compound 16h) is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively[1].

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK
Signaling Pathways >> Epigenetics >> JAK
Signaling Pathways >> Stem Cell/Wnt >> JAK
Research Areas >> Others

[Target]

IC50: 0.7 nM/23.2 nM (JAK2/JAK3)[1].


[References]

[1]. Wang Y, et al. Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors. Bioorg Med Chem. 2017 Jan 1;25(1):75-83.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H27N5O4S

[ Molecular Weight ]:
469.56

Related Compounds