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IL-17A inhibitor 1

Names

[ CAS No. ]:
2452464-73-0

[ Name ]:
IL-17A inhibitor 1

Biological Activity

[Description]:

IL-17A inhibitor 1 (example 24) is a IL-17A inhibitor, with IC50 values of <9.45 nM and 9.3 nM in alphalisa assay and HT-29 cells[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[In Vivo]

IL-17A inhibitor 1 (example 24) possesses high oral bioavailability (F=107%)[1].

[References]

[1]. COATES DAVID ANDREW, et al. IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS. Patent WO2020146194.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H27F5N8O4

[ Molecular Weight ]:
586.51

Related Compounds