2-Oxiraneoctanoic acid,3-octyl-

Names

[ Name ]:
2-Oxiraneoctanoic acid,3-octyl-

[Synonym ]:
3-Octyloxiraneoctanoic Acid
3-octyl-oxiraneoctanoicaci
TRANS-9,10-EPOXYSTEARIC ACID
9,10-epoxystearicacid
OCTADECANOICACID,9,10-EPOXY
Epoxystearic acid
Oxidized oleic acid
9,10-epoxy-octadecanoicaci
9,10-epoxyoctadecanoicacid
oleicacidepoxide
monoepoxy stearic acid

Chemical & Physical Properties

[ Density]:
0.956g/cm3

[ Boiling Point ]:
422.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₈H₃₄O₃

[ Molecular Weight ]:
298.46100

[ Flash Point ]:
141.1ºC

[ Exact Mass ]:
298.25100

[ PSA ]:
49.83000

[ LogP ]:
5.31970

[ Index of Refraction ]:
1.467

[ Storage condition ]:
−20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RG1300000

CHEMICAL NAME :: Octadecanoic acid, 9,10-epoxy-

CAS REGISTRY NUMBER :: 2443-39-2

LAST UPDATED :: 199512

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C18-H34-O3

MOLECULAR WEIGHT :: 298.52

WISWESSER LINE NOTATION :: T3OTJ B8 C7VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2880 mg/kg/24W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 31,41,1963 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,153,1976 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,153,1976 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
RG1300000

[ HS Code ]:
2918990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

GC-MS/MS and LC-MS/MS studies on unlabelled and deuterium-labelled oleic acid (C18:1) reactions with peroxynitrite (O=N-O-O⁻) in buffer and hemolysate support the pM/nM-range of nitro-oleic acids in human plasma.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 964 , 172-9, (2014)

Oleic acid (cis-9,10-octadecenoic acid) is the most abundant monounsaturated fatty acid in human blood. Peroxynitrite (ONOO(-)) is a short-lived species formed from the reaction of nitric oxide (NO) a...

Cloning, functional expression, and characterization of CYP709C1, the first sub-terminal hydroxylase of long chain fatty acid in plants. Induction by chemicals and methyl jasmonate.

J. Biol. Chem. 280(43) , 35881-9, (2005)

We cloned and characterized CYP709C1, a new plant cytochrome P450 belonging to the P450 family, that so far has no identified function except for clustering with a fatty acid metabolizing clade of P45...

Determination of 9,10-epoxystearate ester in intravenous solutions stored in poly(vinyl chloride) bags, using gas chromatography-single-ion monitoring mass spectrometry.

Analyst 109(7) , 967-8, (1984)