Lepunafusp alfa

Names

[ Name ]:
Lepunafusp alfa

Biological Activity

[Description]:

Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Jeong GU, et al. Non-clinical evaluation of a blood-brain barrier-penetrating enzyme for the treatment of mucopolysaccharidosis type I. Molecular Genetics and Metabolism. 2019. 126 (2), S83-S84.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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