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Polyphemusin II-Derived Peptide

Names

[ CAS No. ]:
229030-20-0

[ Name ]:
Polyphemusin II-Derived Peptide

Biological Activity

[Description]:

Polyphemusin II-Derived Peptide (T140), a CXCR4 inhibitor, shows high inhibitory activity against HIV-1 entry and the inhibitory effect on the binding of an anti-CXCR4 monoclonal antibody (12G5) to CXCR4[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> GPCR/G Protein >> CXCR
Signaling Pathways >> Immunology/Inflammation >> CXCR

[References]

[1]. H Tamamura, et al. A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140. Biochem Biophys Res Commun. 1998 Dec 30;253(3):877-82.  

Chemical & Physical Properties

[ Molecular Formula ]:
C90H141N33O18S2

Related Compounds