Mal-Phe-C4-VC-PAB-DMEA-PNU-159682

Names

[ CAS No. ]:
2259318-54-0

[ Name ]:
Mal-Phe-C4-VC-PAB-DMEA-PNU-159682

Biological Activity

[Description]:

Mal-Phe-C4-VC-PAB-DMEA-PNU-159682, a drug-linker conjugate for ADC, consists the ADC linker Mal-Phe-C4-VC-PAB and a potent ADC cytotoxin DMEA-PNU-159682. DMEA-PNU-159682 includes metabolites of nemorubicin (MMDX) from liver microsomes and ADC cytotoxin PNU-159682[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

Chemical & Physical Properties

[ Molecular Formula ]:
C70H83N9O22

[ Molecular Weight ]:
1402.46

Related Compounds