(3S,5R)-Fluvastatin D6 sodium

Names

[ CAS No. ]:
2249799-35-5

[ Name ]:
(3S,5R)-Fluvastatin D6 sodium

Biological Activity

[Description]:

(3S,5R)-Fluvastatin D6 sodium is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1]

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)

[References]

[1]. Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H19D6FNNaO4

[ Molecular Weight ]:
439.48

Related Compounds