<Suppliers Price>

5-(N,N)-Dimethylamiloride Hydrochloride

Names

[ CAS No. ]:
2235-97-4

[ Name ]:
5-(N,N)-Dimethylamiloride Hydrochloride

[Synonym ]:
3-Amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)-2-pyrazinecarboxamide hydrochloride (1:1)
2-Pyrazinecarboxamide, 3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)-, hydrochloride (1:1)
(3-AMINO-5-DIMETHYLAMINO-6-CHLOROPYRAZINOYL)GUANIDINE HYDROCHLORIDE
3-Amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazine-2-carboxamide hydrochloride (1:1)

Biological Activity

[Description]:

Dimethylamiloride hydrochloride is a Na+/H+ exchanger NHE inhibitor with Ki values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively. Dimethylamiloride hydrochloride can be used for pain research[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Masereel B, et al. An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem. 2003 Jun;38(6):547-54.  

Chemical & Physical Properties

[ Molecular Formula ]:
C8H13Cl2N7O

[ Molecular Weight ]:
294.141

[ Exact Mass ]:
293.055878

[ PSA ]:
136.51000

[ LogP ]:
1.97560

Related Compounds