2235-97-4

2235-97-4 structure

Name: 5-(N,N)-Dimethylamiloride Hydrochloride
Chemical Name: (3-amino-5-dimethylamino-6-chloropyrazinoyl)guanidine hydrochloride
CAS Number: 2235-97-4
Molecular Formula: C₈H₁₃Cl₂N₇O
Molecular Weight: 294.141
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-03-13 15:19:24
Modify Date: 2025-08-27 18:47:27
Dimethylamiloride hydrochloride is a Na+/H+ exchanger NHE inhibitor with Ki values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively. Dimethylamiloride hydrochloride can be used for pain research[1].

Name	(3-amino-5-dimethylamino-6-chloropyrazinoyl)guanidine hydrochloride
Synonyms	3-Amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)-2-pyrazinecarboxamide hydrochloride (1:1) 2-Pyrazinecarboxamide, 3-amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)-, hydrochloride (1:1) (3-AMINO-5-DIMETHYLAMINO-6-CHLOROPYRAZINOYL)GUANIDINE HYDROCHLORIDE 3-Amino-6-chloro-N-(diaminomethylene)-5-(dimethylamino)pyrazine-2-carboxamide hydrochloride (1:1)

Description	Dimethylamiloride hydrochloride is a Na+/H+ exchanger NHE inhibitor with Ki values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively. Dimethylamiloride hydrochloride can be used for pain research[1].
Related Catalog	Research Areas >> Inflammation/Immunology
References	[1]. Masereel B, et al. An overview of inhibitors of Na(+)/H(+) exchanger. Eur J Med Chem. 2003 Jun;38(6):547-54.