MtTMPK-IN-4

Names

[ Name ]:
MtTMPK-IN-4

Biological Activity

[Description]:

MtTMPK-IN-4 (compound 2), a para-piperidine, is a potent mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 of 6.1 μM. MtTMPK-IN-4 is a potent tyrosinase inhibitor. MtTMPK-IN-4 is a potent antibacterial agent[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Lijun Song, et al. Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors. J Med Chem. 2018 Apr 12;61(7):2753-2775.

[2]. Jin Li, et al. Recent advances in the design and discovery of synthetic tyrosinase inhibitors. Eur J Med Chem. 2021 Nov 15;224:113744.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₅N₃O₃

[ Molecular Weight ]:
391.46

Related Compounds

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