SPX-101
Names
[ CAS No. ]:
2219362-20-4
[ Name ]:
SPX-101
Biological Activity
[Description]:
SPX-101 is a specific, peptide mimetic promoter of epithelial sodium channel (ENaC) internalization, binds selectively to ENaC and promotes internalization of the α-, β-, and γ-subunits; promotes durable reduction of ENaC membrane concentration, increases mucus transport in the β-ENaC mouse model as well as the sheep model of CF. Fibrosis Phase 2 Clinical
[References]
References 1. Scott DW, et al. Am J Respir Crit Care Med. 2017 Sep 15;196(6):734-744. 2. Lennox A, et al. Am J Respir Crit Care Med. 2017 Sep 15;196(6):671-672. View Related Products by Target Sodium Channel Fibrosis
Chemical & Physical Properties
[ Molecular Formula ]:
C53H90N14O16
[ Molecular Weight ]:
1179.385