TSHR antagonist S37b

Names

[ Name ]:
TSHR antagonist S37b

Biological Activity

[Description]:

TSHR antagonist S37b is an enantiomer of TSHR antagonist S37a (HY-129995A), shows only a minor effect for TSHR inhibition. TSHR antagonist S37b can be used for the research of thyroid function[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> TSH Receptor

[Target]

TSHR[1]

[References]

[1]. Marcinkowski P, et al. A New Highly Thyrotropin Receptor-Selective Small-Molecule Antagonist with Potential for the Treatment of Graves' Orbitopathy. Thyroid. 2019 Jan;29(1):111-123.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₀N₂O₃S₂

[ Molecular Weight ]:
460.57

Related Compounds

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