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IMPDH2-IN-5

Names

[ CAS No. ]:
2119603-25-5

[ Name ]:
IMPDH2-IN-5

Biological Activity

[Description]:

A potent, selective IMPDH2 inhibitor that covalently binds to Cys140 with IC50 of 620 nM (inhibition of NO production); a Sappanone A derivative.

[References]

References 1. Liao LX, et al. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5986-E5994. View Related Products by Target IMPDH

Chemical & Physical Properties

[ Molecular Formula ]:
C16H11FO5

[ Molecular Weight ]:
302.257


Related Compounds

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