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Cinnamyl piperazine hydrochloride

Names

[ CAS No. ]:
2101626-26-8

[ Name ]:
Cinnamyl piperazine hydrochloride

[Synonym ]:
GSK-2894631A

Biological Activity

[Description]:

HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC50 of 9.9 nM[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> PGE synthase

[Target]

IC50: 9.9 nM (H-PGDS)[1]


[References]

[1]. Deaton DN, et al. The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1456-1478.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H24F2N2O3

[ Molecular Weight ]:
378.41

Related Compounds