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2101626-26-8

2101626-26-8 structure
2101626-26-8 structure

Name HPGDS inhibitor 2
Synonyms GSK-2894631A
Description HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC50 of 9.9 nM[1].
Related Catalog
Target

IC50: 9.9 nM (H-PGDS)[1]

References

[1]. Deaton DN, et al. The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1456-1478.

Molecular Formula C20H24F2N2O3
Molecular Weight 378.41