AT-090
Names
[ CAS No. ]:
2099681-59-9
[ Name ]:
AT-090
Biological Activity
[Description]:
AT-090 is a novel potent, selective nociceptin/orphanin FQ receptor (NOP receptor) agonist with Ki of 5.61 nM; displays >15-fold selectivity over mu, and >40-fold over kappa opioid receptors; induces concentration dependent contractions of the mouse colon tissues with potency and efficacy similar to N/OFQ; a useful pharmacological tool for investigating the therapeutic potential of NOP partial agonists.
[References]
References 1. Ferrari F, et al. Eur J Pharmacol. 2016 Dec 15;793:1-13. 2. Asth L, et al. Neuropharmacology. 2016 Jun;105:434-442. View Related Products by Target Opioid Receptor
Chemical & Physical Properties
[ Molecular Formula ]:
C22H30N2O2
[ Molecular Weight ]:
354.494