KGP-420

Names

[ CAS No. ]:
2082762-29-4

[ Name ]:
KGP-420

Biological Activity

[Description]:

KGP-420 is the water-soluble phosphate prodrug of KGP-94 in vivo studies, KGP-94 is a potent, selective cathepsin L inhibitor with IC50 of 189 nM; readily converts to KGP-94, and shows cytotoxicity against HUVECs with GI50 of 20.2 uM.

[References]

References 1. Parker EN, et al. Bioorg Med Chem Lett. 2017 Mar 1;27(5):1304-1310. View Related Products by Target Cathepsin

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₃BrN₃Na₂O₄PS

[ Molecular Weight ]:
476.192

Related Compounds

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