<Suppliers Price>

Diacetyldichlorofluorescein

Names

[ CAS No. ]:
2044-85-1

[ Name ]:
Diacetyldichlorofluorescein

[Synonym ]:
2',7'-DICHLOROFLUORESCIN DIACETATE
2`,7`-Dichlorofluorescein diacetate
2',7'-dichlorodihydrofluorescein diacetate
Leukodiacetyl-2,7-dichlorofluorescein
2‘,7‘-Dichlorofluorescein 3‘,6‘-diacetate
DCFDA
2′,7′-Dichlorofluorescein diacetate
diacetyldichlorofluorescin
Leuco-dcf diacetate
Diacetyldichlorofluorescein
Dcfh-DA
MFCD00037501

Biological Activity

[Description]:

2′,7′-Dichlorofluorescein diacetate (DCFH-DA) is a cell-permeable fluorescent probe. 2′,7′-Dichlorofluorescein diacetate can be used to detect the generation of reactive oxygen intermediates and for assessing the overall oxidative stress in toxicological phenomenon[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Afri M, et al. Active oxygen chemistry within the liposomal bilayer. Part IV: Locating 2',7'-dichlorofluorescein (DCF), 2',7'-dichlorodihydrofluorescein (DCFH) and 2',7'-dichlorodihydrofluorescein diacetate (DCFH-DA) in the lipid bilayer. Chem Phys Lipids. 2004 Aug;131(1):123-33.

Chemical & Physical Properties

[ Density]:
1.59 g/cm3

[ Boiling Point ]:
657.9ºC at 760 mmHg

[ Melting Point ]:
232-234ºC(lit.)

[ Molecular Formula ]:
C24H14Cl2O7

[ Molecular Weight ]:
485.27000

[ Flash Point ]:
239.2ºC

[ Exact Mass ]:
484.01200

[ PSA ]:
88.13000

[ LogP ]:
5.41200

[ Vapour Pressure ]:
3.49E-17mmHg at 25°C

[ Index of Refraction ]:
1.692

[ Storage condition ]:
2~8°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;C: Corrosive;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

[ HS Code ]:
2932999099

Precursor & DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Chronic low level arsenic exposure evokes inflammatory responses and DNA damage.

Int. J. Hyg. Environ. Health 218 , 564-74, (2015)

The cross-sectional study investigated the impact of chronic low level arsenic (As) exposure (11-50μg/L) on CD14 expression and other inflammatory responses in rural women of West Bengal enrolled from...

JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells.

Oncotarget 6(1) , 458-70, (2015)

Chemoresistance associated with cancer stem cells (CSCs), which is now being held responsible for the pervasive therapy resistance of pancreatic cancer, poses a major challenge to the successful manag...

NADPH oxidase mediated maneb- and paraquat-induced oxidative stress in rat polymorphs: Crosstalk with mitochondrial dysfunction.

Pestic. Biochem. Physiol. 123 , 74-86, (2015)

Oxidative stress is a key factor in Parkinson's disease (PD) pathogenesis. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase and impaired mitochondrion regulate oxidative stress-mediated man...


More Articles