D(-)-Norvaline

Names

[ CAS No. ]:
2013-12-9

[ Name ]:
D(-)-Norvaline

[Synonym ]:
(R)-(−)-2-Aminopentanoic acid
D-Nva
H-D-Nva-OH
D-2-amino-pentanoate
NORVALINE, D-
D-2-Aminopentanoic acid
D(-)-Norvaline
D-norVal-OH
D-Norvaline
(R)-2-Aminopentanoic acid,(R)-2-Aminovaleric acid
(R)-(-)-2-Aminopentanoic acid
Norvaline
MFCD00008097
(R)-2-Aminopentanoic acid
(2R)-2-aminopentanoic acid
(R)-2-Aminovaleric Acid
EINECS 217-936-2
(R)-norvaline
D-2-Aminovaleric acid
D-Ape

Biological Activity

[Description]:

D-Norvaline is a valine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
222.9±23.0 °C at 760 mmHg

[ Melting Point ]:
300ºC

[ Molecular Formula ]:
C₅H₁₁NO₂

[ Molecular Weight ]:
117.146

[ Flash Point ]:
88.6±22.6 °C

[ Exact Mass ]:
117.078979

[ PSA ]:
63.32000

[ LogP ]:
0.38

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.464

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).

Bioorg. Med. Chem. 19 , 6409-18, (2011)

The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...