UCL-1848 trifluoroacetate salt

Names

[ CAS No. ]:
201147-53-7

[ Name ]:
UCL-1848 trifluoroacetate salt

[Synonym ]:
8,14-Diaza-1,7(1,4)-diquinolinacyclotetradecaphane trifluoroacetate salt

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₄H₃₅F₉N₄O₆

[ Molecular Weight ]:
766.65100

[ Exact Mass ]:
766.24100

[ PSA ]:
146.48000

[ LogP ]:
6.22290

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

Articles

bis-Quinolinium cyclophanes: 8,14-diaza-1,7(1, 4)-diquinolinacyclotetradecaphane (UCL 1848), a highly potent and selective, nonpeptidic blocker of the apamin-sensitive Ca(2+)-activated K(+) channel.

J. Med. Chem. 43 , 3478-3481, (2000)

Therapeutic scope of modulation of non-voltage-gated cation channels.

Drug Discov. Today 10 , 129-137, (2005)

Although widely regarded as attractive drug targets, less than a tenth of known ion channels are currently commercially exploited as therapeutic targets. Historically, drug discovery efforts on ion ch...