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Pseudin-2 trifluoroacetate salt

Names

[ CAS No. ]:
388602-02-6

[ Name ]:
Pseudin-2 trifluoroacetate salt

[Synonym ]:
MFCD11975009

Biological Activity

[Description]:

Pseudin-2, an AMP thast could be isolated from the skin of the South American paradoxical frog Pseudis paradoxa, exert a potent growth inhibitory effect against Gram-negative bacteria[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Pseudin-2 对大多数细菌的MIC 值为 2-4μM,除了对P. aeruginosa 的MIC 值为 8 μM。Pseudin-2对耐药菌和病原真菌细胞有很强的抗菌活性。

[References]

[1]. Seong-Cheol Park, et al. A plausible mode of action of pseudin-2, an antimicrobial peptide from Pseudis paradoxa. Biochim Biophys Acta. 2011 Jan;1808(1):171-82.  

Chemical & Physical Properties

[ Molecular Formula ]:
C122H202N36O32


Related Compounds

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