2-Bromo-4'-cyanoacetophenone

Names

[ CAS No. ]:
20099-89-2

[ Name ]:
2-Bromo-4'-cyanoacetophenone

[Synonym ]:
2-bromo-4'-cyano-acetophenone
Benzonitrile, 4-(bromoacetyl)-
MFCD00052931
4-(Bromacetyl)benzolcarbonitril
2-bromo-4'-CN-acetophenone
4-(Bromoacetyl)benzonitrile
2-Bromo-4'-cyanoacetophenone
p-Cyanophenacyl bromide
2-Br-4'-CN-acetophenone
4-(2-Bromoacetyl)benzonitrile
4-Cyanophenacyl bromide
Benzonitrile, 4-(2-bromoacetyl)-
4-(2-bromo-acetyl)-benzonitrile

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
342.4±22.0 °C at 760 mmHg

[ Melting Point ]:
92-96 °C(lit.)

[ Molecular Formula ]:
C₉H₆BrNO

[ Molecular Weight ]:
224.054

[ Flash Point ]:
160.9±22.3 °C

[ Exact Mass ]:
222.963272

[ PSA ]:
40.86000

[ LogP ]:
1.75

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.590

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H312-H314-H332

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R20/21/22;R34

[ Safety Phrases ]:
S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 2928 6.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Direct synthesis of α-bromoketones from alkylarenes by aerobic visible light photooxidation.

Org. Biomol. Chem. 8(20) , 4701-4, (2010)

The direct synthesis of α-bromoketones from alkylarenes by aerobic photooxidation with hydrobromic acid is reported. The key success for this direct oxidative reaction is due to control of bromination...

Application of DMF–methyl sulfate adduct in the regioselective synthesis of 3-acylated indolizines. Przewloka T, et al.

Tetrahedron Lett. 48(33) , 5739-5742, (2007)

Synthesis and antifungal activity of novel thiazole-containing triazole antifungals. II. Optically active ER-30346 and its derivatives. Tsuruoka, Akihiko, et al.

Chem. Pharm. Bull. 46(4) , 623-630, (1998)