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NKP-1339

Names

[ CAS No. ]:
197723-00-5

[ Name ]:
NKP-1339

[Synonym ]:
sodium trans-tetrachlorobis(indazole)ruthenate(III)
Na[trans-RuCl4(1H-indazole)2]
Na[trans-RuCl4(indazole)2]
KP1339
sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)]
NKP-1339

Biological Activity

[Description]:

NKP-1339(IT-139) is a ruthenium(iii) coordination anticancer compound based on target to transferrin.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer

[References]

[1]. Kuhn PS, et al. Improved reaction conditions for the synthesis of new NKP-1339 derivatives and preliminary investigations on their anticancer potential. Dalton Trans. 2014 Nov 11.

[2]. Robert Trondl, et al. ChemInform Abstract: NKP-1339, the First Ruthenium-Based Anticancer Drug on the Edge to Clinical Application.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Molecular Formula ]:
C14H12Cl4N4NaRu

[ Molecular Weight ]:
502.14400

[ Exact Mass ]:
500.87600

[ PSA ]:
41.44000

[ LogP ]:
5.88380

[ Storage condition ]:
2-8℃

Related Compounds