2-NP-AOZ

Names

[ CAS No. ]:
19687-73-1

[ Name ]:
2-NP-AOZ

[Synonym ]:
2-nitrophenylmethylene-3-amino-2-oxazolidinone
2-NP-AOZ

Biological Activity

[Description]:

2-NP-AOZ is a 2-nitrophenyl derivative of AOZ (HY-W012982, a tissue-bound metabolite of the Furazolidone). 2-NP-AOZ can be used to determination of the AOZ residues[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Cheng CC, et, al. Development and residue screening of the furazolidone metabolite, 3-amino-2-oxazolidinone (AOZ), in cultured fish by an enzyme-linked immunosorbent assay. J Agric Food Chem. 2009 Jul 8;57(13):5687-92.

[2]. Li Z, et, al. Simultaneous detection of four nitrofuran metabolites in honey by using a visualized microarray screen assay. Food Chem. 2017 Apr 15;221:1813-1821.

Chemical & Physical Properties

[ Density]:
1.45g/cm3

[ Boiling Point ]:
380.8ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₉N₃O₄

[ Molecular Weight ]:
235.19600

[ Flash Point ]:
184.1ºC

[ Exact Mass ]:
235.05900

[ PSA ]:
87.72000

[ LogP ]:
1.84200

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.645

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RQ4225100

CHEMICAL NAME :: 2-Oxazolidone, 3-((o-nitrophenyl)methyleneamino)-

CAS REGISTRY NUMBER :: 19687-73-1

LAST UPDATED :: 199610

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H9-N3-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2201 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 24,737,1989

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
RQ4225100

Articles

A. Conneely et al.

Anal. Chim. Acta 483 , 91, (2003)