2-NP-AMOZ

Names

[ Name ]:
2-NP-AMOZ

[Synonym ]:
5-(4-Morpholinylmethyl)-3-[(E)-(2-nitrobenzylidene)amino]-1,3-oxazolidin-2-one
2-Oxazolidinone, 5-(4-morpholinylmethyl)-3-[[(1E)-(2-nitrophenyl)methylene]amino]-

Biological Activity

[Description]:

2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ (a metabolite of antibiotic Furaltadone), can be used to detect protein bound AMOZ[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Sheu SY, et, al. Development of a competitive ELISA for the detection of a furaltadone marker residue, 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), in cultured fish samples. J Vet Med Sci. 2012 Nov;74(11):1439-46.

[2]. Li Z, et, al. Simultaneous detection of four nitrofuran metabolites in honey by using a visualized microarray screen assay. Food Chem. 2017 Apr 15;221:1813-1821.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
485.2±53.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₈N₄O₅

[ Molecular Weight ]:
334.327

[ Flash Point ]:
247.3±30.9 °C

[ Exact Mass ]:
334.127716

[ PSA ]:
100.19000

[ LogP ]:
0.89

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.652

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Articles

Analysis of protein-bound metabolites of furazolidone and furaltadone in pig liver by high-performance liquid chromatography and liquid chromatography-mass spectrometry.

Analyst 121 , 1463, (1996)

Studies undertaken using radiolabelled furazolidone have demonstrated the covalent binding of residues of the drug to cellular protein in vivo. A portion of these bound residues and those formed by fu...

Related Compounds

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