LY 338979

Names

[ CAS No. ]:
193281-00-4

[ Name ]:
LY 338979

[Synonym ]:
N-[4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid
2-{4-[2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethyl]-benzoylamino}-pentanedioic acid
LY 338979
Pemetrexed Impurity 18

Biological Activity

[Description]:

LY-338979 (Pemetrexed 6-oxo diacid impurity) is a metabolite of LY231514 (Pemetrexed; HY-10820)[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Woodland JM, et al. Metabolism and disposition of the antifolate LY231514 in mice and dogs. Drug Metab Dispos. 1997 Jun;25(6):693-700.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₁N₅O₇

[ Molecular Weight ]:
443.41

[ Exact Mass ]:
443.14400

[ PSA ]:
209.05000

[ LogP ]:
0.88680

Synthetic Route

Click to get detail synthetic route

Related Compounds

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