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E3 Ligase Ligand-Linker Conjugates 2

Names

[ CAS No. ]:
1818885-63-0

[ Name ]:
E3 Ligase Ligand-Linker Conjugates 2

[Synonym ]:
1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-[2-[2-(4-aminophenoxy)ethoxy]ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-
4-{[2-(2-{2-[2-(4-Aminophenoxy)ethoxy]ethoxy}ethoxy)ethyl]amino}-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione

Biological Activity

[Description]:

E3 Ligase Ligand-Linker Conjugates 2 incorporates a ligand for the E3 ubiquitin ligase, and a PROTAC linker, which bring together target protein and ubiquitinating machinery.

[Related Catalog]:

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate
Research Areas >> Cancer

[Related Small Molecules]

E3 ligase Ligand-Linker Conjugates 14 | E3 Ligase Ligand-Linker Conjugates 1 | E3 ligase Ligand-Linker Conjugates 17 | E3 ligase Ligand-Linker Conjugates 16 | (SRS)-AHPC-PEG3-NH2 hydrochloride | E3 ligase Ligand-Linker Conjugates 6 | E3 ligase Ligand-Linker Conjugates 18 | E3 ligase Ligand-Linker Conjugates 4 | (SRS)-AHPC-PEG4-NH2 hydrochloride | E3 Ligase Ligand-Linker Conjugates 22 | E3 ligase Ligand-Linker Conjugates 10 | E3 ligase Ligand-Linker Conjugates 13 | E3 Ligase Ligand-Linker Conjugates 24 TFA | E3 ligase Ligand-Linker Conjugates 11

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
792.0±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C27H32N4O8

[ Molecular Weight ]:
540.565

[ Flash Point ]:
432.8±32.9 °C

[ Exact Mass ]:
540.221985

[ LogP ]:
-0.71

[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C

[ Index of Refraction ]:
1.625

Related Compounds