E3 ligase Ligand-Linker Conjugates 11

E3 Ligase Ligand-Linker Conjugate 11 is a synthesized compound which incorporates a ligand for the E3 ubiquitin ligase and a PROTAC linker to bring together target protein and ubiquitinating machinery.

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

Research Areas >> Cancer

[1]. Ashton C. Lai, et al. Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL. Angew Chem Int Ed Engl. 2016 Jan 11; 55(2): 807–810.

E3 ligase Ligand-Linker Conjugates 14 | E3 Ligase Ligand-Linker Conjugates 1 | E3 ligase Ligand-Linker Conjugates 17 | E3 ligase Ligand-Linker Conjugates 16 | (SRS)-AHPC-PEG3-NH2 hydrochloride | E3 ligase Ligand-Linker Conjugates 6 | E3 ligase Ligand-Linker Conjugates 18 | E3 Ligase Ligand-Linker Conjugates 2 | E3 ligase Ligand-Linker Conjugates 4 | (SRS)-AHPC-PEG4-NH2 hydrochloride | E3 Ligase Ligand-Linker Conjugates 22 | E3 ligase Ligand-Linker Conjugates 10 | E3 ligase Ligand-Linker Conjugates 13 | E3 Ligase Ligand-Linker Conjugates 24 TFA