sEH inhibitor-3

Names

[ CAS No. ]:
1809885-35-5

[ Name ]:
sEH inhibitor-3

Biological Activity

[Description]:

sEH inhibitor-3 (compound 35) is a potent and orally active soluble epoxide hydrolase (sEH) inhibitor with a Ki of 0.75 nM for human sEH[1].

[Related Catalog]:

Research Areas >> Neurological Disease

[Target]

Ki: 0.75 nM (Human sEH)[1]


[References]

[1]. Kin Sing Stephen Lee, et al. Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain. Bioorg Med Chem. 2020 Nov 15;28(22):115735.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H23F4N3O4

[ Molecular Weight ]:
433.40

Related Compounds