GPA 512

Names

[ Name ]:
GPA 512

Biological Activity

[Description]:

The orally bioavailable prodrug of Galiellalactone, a direct inhibitor of STAT3, prevents the transcription of STAT3 regulated genes; increases the plasma exposure of the active parent compound 20-fold compared to Galiellalactone; significantly reduces tumor growth in DU145 xenograft tumors.

[References]

References 1. Escobar Z, et al. J Med Chem. 2016 May 26;59(10):4551-62. View Related Products by Target STAT

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₂₅NO₆S

[ Molecular Weight ]:
371.448

Related Compounds

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