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DMEA-PNU-159682

Names

[ CAS No. ]:
1799421-48-9

[ Name ]:
DMEA-PNU-159682

Biological Activity

[Description]:

DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Daunorubicins/Doxorubicins


[References]

[1]. Chen Jingkang, et al. Disubstituted maleic amide class connexon for antibody-drug conjugate and its preparation method and application. CN108101825A.

[2]. John Flygare, et al. Anthracycline disulfide intermediates, antibody-drug conjugates and methods. WO2016040825A1

Chemical & Physical Properties

[ Molecular Formula ]:
C37H45N3O14

[ Molecular Weight ]:
755.76

Related Compounds