Seco-DUBA hydrochloride

Names

[ CAS No. ]:
1795733-93-5

[ Name ]:
Seco-DUBA hydrochloride

Biological Activity

[Description]:

Seco-DUBA hydrochloride is a toxin for ADC drug SYD985[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin

Research Areas >> Inflammation/Immunology

[References]

[1]. Ronald C Elgersma, et al. Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody-Drug Conjugate SYD985. Mol Pharm. 2015 Jun 1;12(6):1813-35.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₂₃ClN₄O_4.xClH

Related Compounds

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