Viquidil hydrochloride

Names

[ Name ]:
Viquidil hydrochloride

[Synonym ]:
6-methoxy-1,5-naphthyridin-4-ol
6'-methoxy-1,8-seco-cinchonan-9-one,hydrochloride
6-methoxy-1,5-naphthyridine-4-ol
Quinotoxine Hydrochloride
6'-Methoxy-1,8-seco-cinchonan-9-on,Hydrochlorid
chlorhydrate de quinotoxine
1,5-Naphthyridin-4-ol,6-methoxy

Biological Activity

[Description]:

Viquidil hydrochloride (Quinotoxine hydrochloride), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil hydrochloride shows antithrombotic activity[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[In Vivo]

Viquidil hydrochloride (Quinotoxine hydrochloride) increases the cerebral blood flow in the rabbit considerably[3].

[References]

[1]. Lecrubier C,et al. [Effect of a new cerebral vasodilator agent, viquidil, on the aggregation of blood platelets]. Arzneimittelforschung. 1972 Aug;22(8):1334-6.

[2]. Sim AK, et al. The antithrombotic activity of viquidil, a cerebral vasodilator. Arzneimittelforschung. 1979;29(3):508-11.

[3]. De Valois JC. Increase in cerebral blood flow in the rabbit by viquidil. Stroke. 1973 Mar-Apr;4(2):218-20.

Chemical & Physical Properties

[ Density]:
1.125g/cm3

[ Boiling Point ]:
493.1ºC at 760mmHg

[ Molecular Formula ]:
C₂₀H₂₅ClN₂O₂

[ Molecular Weight ]:
360.87800

[ Flash Point ]:
252ºC

[ Exact Mass ]:
360.16000

[ PSA ]:
51.22000

[ LogP ]:
4.74880

Related Compounds

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