Boc-His-OH

Names

[ Name ]:
Boc-His-OH

[Synonym ]:
tert-Butyloxycarbonyl-L-histidine
Nalpha-BOC-L-Histidine
n|A-boc-l-histidine
MFCD00065576
Na-(tert-Butoxycarbonyl)-L-histidine
Boc-His-OH
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-histidine
N-Boc-histidine
Nα-(tert-Butoxycarbonyl)-L-histidine
L-Histidine, N-[(1,1-dimethylethoxy)carbonyl]-
Nalpha-(tert-Butoxycarbonyl)-L-histidine
Boc-L-Histidine
N-(tert-Butoxycarbonyl)-L-histidine
EINECS 241-768-9
N-Boc-L-histidine
Nα-boc-L-histidine

Biological Activity

[Description]:

N-tert-Butyloxycarbonyl-L-histidine is a histidine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
522.2±45.0 °C at 760 mmHg

[ Melting Point ]:
195 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₁H₁₇N₃O₄

[ Molecular Weight ]:
255.270

[ Flash Point ]:
269.6±28.7 °C

[ Exact Mass ]:
255.121902

[ PSA ]:
104.31000

[ LogP ]:
0.58

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.542

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Nat. Chem. Biol. 5 , 45-52, (2009)

Transporter-related nutrient sensors, called transceptors, mediate nutrient activation of signaling pathways through the plasma membrane. The mechanism of action of transporting and nontransporting tr...

Exploring advantages/disadvantages and improvements in overcoming gene delivery barriers of amino acid modified trimethylated chitosan.

Pharm. Res. 32 , 2038-50, (2015)

Present study aimed at exploring advantages/disadvantages of amino acid modified trimethylated chitosan in conquering multiple gene delivery obstacles and thus providing comprehensive understandings f...