NDH-1 inhibitor-1

Names

[ CAS No. ]:
173964-49-3

[ Name ]:
NDH-1 inhibitor-1

[Synonym ]:
2-Naphthalenecarboxamide, N-[(3,4-dimethoxyphenyl)methyl]-

Biological Activity

[Description]:

NDH-1 inhibitor-1 (compound 27) is a potent NDH-1 inhibitor with pI50 values of <4, 5.40, 6.15 µM for Bovine SMP (submitochondrial particles), Potato SMP and E. coli, respectively[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

NDH-1[1]


[References]

[1]. Satoh T, et al. Comparison of the inhibitory action of synthetic capsaicin analogues with various NADH-ubiquinone oxidoreductases. Biochim Biophys Acta. 1996 Jan 11;1273(1):21-30.  

Chemical & Physical Properties

[ Density]:
1.178±0.06 g/cm3(Predicted)

[ Boiling Point ]:
564.1±40.0 °C(Predicted)

[ Molecular Formula ]:
C20H19NO3

[ Molecular Weight ]:
321.4

Related Compounds