α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Names

[ Name ]:
α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

[Synonym ]:
N-Acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide trifluoroacetate (1:1)
L-Valinamide, N-acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-, compd. with 2,2,2-trifluoroacetic acid (1:1)

Biological Activity

[Description]:

α-Melanocyte-Stimulating Hormone (MSH), amide TFA is an endogenous neuropeptide, with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC), acts as an endogenous melanocortin receptor 4 (MC4R) agonist[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor

[Target]

MC4R[2]

[References]

[1]. Madhuri Singh, et al. C-terminal amino acids of alpha-melanocyte-stimulating hormone are requisite for its antibacterial activity against Staphylococcus aureus. Antimicrob Agents Chemother. 2011 May;55(5):1920-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₉H₁₁₀F₃N₂₁O₂₁S

[ Molecular Weight ]:
1778.907

[ Exact Mass ]:
1777.785767

Related Compounds

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