(2H7)Isoquinoline

Names

[ CAS No. ]:
17157-12-9

[ Name ]:
(2H7)Isoquinoline

[Synonym ]:
Heptadecylammonium-chlorid
D7-isoquinoline
heptadecan-1-amine hydrochloride
Heptadeuterio-isochinolin
Tetra-n-heptadecylammonium
Isochinolin-d7
heptadecylamine,hydrochloride
(H)Isoquinoline
Isoquinoline-d
Heptadecylamin,Hydrochlorid

Biological Activity

[Description]:

Isoquinoline-d7 is the deuterium labeled Isoquinoline[1]. Isoquinoline is an analog of?pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities[2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Zhi-Xing Qing, et al. Anticancer and Reversing Multidrug Resistance Activities of Natural Isoquinoline Alkaloids and Their Structure-activity Relationship. Curr Med Chem  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
243.2±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C9D7N

[ Molecular Weight ]:
136.202

[ Flash Point ]:
107.2±0.0 °C

[ Exact Mass ]:
136.101791

[ PSA ]:
12.89000

[ LogP ]:
1.96

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.642

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds