Propylparaben-d7

Names

[ CAS No. ]:
1246820-92-7

[ Name ]:
Propylparaben-d7

[Synonym ]:
Benzoic acid, 4-hydroxy-, propyl-d ester
(H)Propyl 4-hydroxybenzoate

Biological Activity

[Description]:

Propylparaben-d7 (Propyl parahydroxybenzoate-d7)is the deuterium labeledPropylparaben(HY-N2026)[1]. Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben disrupts antral follicle growth and steroidogenic function by altering the cell-cycle, apoptosis, and steroidogenesis pathways. Propylparaben also decreases sperm number and motile activity in rats[2][3][4].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
294.3±13.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H5D7O3

[ Molecular Weight ]:
187.24

[ Flash Point ]:
124.6±12.6 °C

[ Exact Mass ]:
187.122574

[ LogP ]:
2.93

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.532